When it comes to airline safety, Quantas has had an impeccable record to say the least. But even an Airline with an impeccable safety record will have problems. In August of 2008 when a particular Quantas flight from Hong Kong to Melbourne experienced a rapid decompression at 20,000 feet, at which time the plane was eventually diverted to Manila where it was found that portions of the fuselage were missing. None of the 346 passengers or the 19 crewmen aboard the aircraft were injured.

This form of explosive decompression has occurred in the past to various airlines on April 28, 1988 an Aloha Airlines 737 lost part of its fuselage on the top part of the cabin area in midair. One flight attendant was killed when she was sucked out of the plane. Another example of explosive decompression occurred on February 28, 1989 when the cargo door and part of the fuselage of a United Airlines 747 separate sucking out nine passengers to their death. Probably one of the most famous airline accidents involving the main fuselage occurred on December 21, 1988 when a bomb exploded in the cargo compartment of a pan am airlines 747, leading to a significant loss of the fuselage followed by an in-flight breakup, killing all 259 people on board the aircraft as well as 11 on the ground.

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